NEWMELAN DAY & NIGHT® by Dr. Eduardo Krulig is the synergistic combination of several assets, acting simultaneously blocking the different stages that are related in the formation of Melasma.NEWMELAN DAY & NIGHT acts in several stages of melanogenesis, inhibiting inflammatory processes, tyrosinase, the process of oxidation of tyrosine and the formation of melanin. It acts at the level of melanocytes, and melanosomes, superficial layers of the skin.